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BEGIN:VEVENT
DTSTART;VALUE=DATE:20230125
DTEND;VALUE=DATE:20230128
DTSTAMP:20260423T003119
CREATED:20221102T093942Z
LAST-MODIFIED:20230111T113621Z
UID:7119-1674604800-1674863999@bifi.es
SUMMARY:XI National Conference BIFI 2023
DESCRIPTION:The XI National Conference BIFI 2023 (http://bifi23.bifi.es) of the Institute for Biocomputation and Physics of Complex Systems  (BIFI) aims at giving all participants the chance to disseminate their work\, and at the same time strengthening existing collaborations or establishing new ones within the different research lines promoted by the BIFI. \nThe format of the congress will include plenary sessions\, with invited and contributed talks\, as well as the corresponding poster sessions. \nMAIN TRACKS: \n\nBiochemistry\, Molecular and Cellular Biology\nPhysics\nBiophysics\nComputation\n\nCALL FOR COMMUNICATIONS \nResearchers from any Institution are warmly invited to attend the meeting\, and submit scientific communications related to the Main Tracks of the event. We could limit the attendees number due to a capacity issue at the conference rooms\, so that\, if necessary\, we might reject applications to participate. \nIMPORTANT DATES \nDates of the Conference: January 25th – January 27th\, 2023.\nRegistration deadline: December 2nd\, 2022.\nAbstract submission deadline: December 2nd\, 2022. \nVENUE \nConference Room\, Edificio I+D\, Campus Río Ebro.
URL:https://bifi.es/schedule/xi-national-conference-bifi-2023/
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221214T100000
DTEND;TZID=Europe/Madrid:20221214T120000
DTSTAMP:20260423T003119
CREATED:20221212T095224Z
LAST-MODIFIED:20221212T095224Z
UID:7154-1671012000-1671019200@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: ANA JIMÉNEZ ALESANCO
DESCRIPTION:“Drug discovery for inhibiting Bacteroides fragilis toxin: from a chemical screening to an animal model”. ANA JIMÉNEZ ALESANCO \nWednesday\, 14 December 2022 \n10:00-12:00 h \nSalón de Actos Edificio I+D
URL:https://bifi.es/schedule/i-cycle-of-young-researcher-seminars-in-the-bio-area-ana-jimenez-alesanco/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221123T100000
DTEND;TZID=Europe/Madrid:20221123T120000
DTSTAMP:20260423T003119
CREATED:20221118T090141Z
LAST-MODIFIED:20221118T090956Z
UID:7134-1669197600-1669204800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS  IN THE BIO AREA: Mario Tovar Calonge
DESCRIPTION:“Forecasting perturbations on mycobacterium tuberculosis transmission with mathematical models: From COVID19-TB syndemics to the evaluation of new vaccines”. MARIO TOVAR CALONGE \nWednesday\, 23 November 2022 \n10:00-12:00 h \nSalón de Actos Edificio I+D
URL:https://bifi.es/schedule/i-ciclo-de-seminarios-jovenes-investigadores-en-el-area-bio-mario-tovar-calonge/
LOCATION:Salon de actos del edificio I+D
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221005T093000
DTEND;TZID=Europe/Madrid:20221005T113000
DTSTAMP:20260423T003119
CREATED:20221025T124545Z
LAST-MODIFIED:20221118T091225Z
UID:7094-1664962200-1664969400@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: ANDRÉS MANUEL GONZÁLEZ RAMÍREZ
DESCRIPTION:“Bases estructurales de la Core 1 sintasa”. ANDRÉS MANUEL GONZÁLEZ RAMÍREZ \nWednesday\, 5 October 2022 \n9:30-11:30 h \nSalón de Actos Edificio I+D
URL:https://bifi.es/schedule/i-cycle-of-seminars-young-researchers-in-the-bio-area-andres-manuel-gonzalez-ramirez/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220914T100000
DTEND;TZID=Europe/Madrid:20220914T120000
DTSTAMP:20260423T003119
CREATED:20220915T120524Z
LAST-MODIFIED:20221118T091314Z
UID:7004-1663149600-1663156800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: Javier Macías León
DESCRIPTION:“Estudio de la acción protectora frente a infecciones fúngicas invasivas de un nanobody dirigido al sitio activa de beta-1\,3.glucanosiltransferasas”. JAVIER MACÍAS LEÓN \nThursday\,14 september\,2022 \n10:00-12:00 h \nAula Edificio I+D
URL:https://bifi.es/schedule/i-ciclo-de-seminarios-jovenes-investigadores-en-el-area-bio-javier-macias-leon/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220616T100000
DTEND;TZID=Europe/Madrid:20220616T120000
DTSTAMP:20260423T003119
CREATED:20220615T063247Z
LAST-MODIFIED:20221118T091346Z
UID:6856-1655373600-1655380800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: PABLO FERNÁNDEZ GARRIDO
DESCRIPTION:“Nuevos métodos en autoorganización e interfases: experimentación\, análisis y simulación”. PABLO FERNÁNDEZ GARRIDO \npablo_f_garrido_a4 \nThursday\,16 June 2022\n10:00-12:00 h\nAula Edificio I+D
URL:https://bifi.es/schedule/i-cycle-of-seminars-young-researchers-bio-area-pablo-fernandez-garrido/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220607T090000
DTEND;TZID=Europe/Madrid:20220609T180000
DTSTAMP:20260423T003119
CREATED:20211027T125134Z
LAST-MODIFIED:20220503T114702Z
UID:6547-1654592400-1654797600@bifi.es
SUMMARY:The International BIFI 2022 Conference
DESCRIPTION:The  International BIFI 2022 Conference will take place online from February 7th to 9th\, 2022. On this occasion the Conference will be focused on the Science of Covid-19: from molecular drug design to data-driven epidemiological models.  \nIn order to ease attendance\, this year’s conference will be entirely hosted online. \nEvery two years the Institute organizes an international conference around its research areas. This is the case of 2022 when we will be holding the BIFI 2022 International Conference which will focus around what we could call the Science of Covid-19. As we well know at this time\, the subject is highly topical and possibly expected\, but given the massive impact to our societies and its relation to the core activities of our institute\, it is also natural choice for 2022. We hope this occasion will serve to consolidate knowledge on the topic\, bring new insights and tools to it\, and also to fill some gaps and open new research paths. The Conference aims at providing a forum to discuss the latest advances and insights in the study of this pandemic. All topics that fit within the science of COVID-19 from a complexity\, biological or interdisciplinary point of view are welcome. \nOn the website of the event (http://bifi22.bifi.es/) to be announced all the necessary information including the access link in due time.
URL:https://bifi.es/schedule/the-international-bifi-2022-conference/
LOCATION:Online
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220601T100000
DTEND;TZID=Europe/Madrid:20220601T120000
DTSTAMP:20260423T003119
CREATED:20220610T112250Z
LAST-MODIFIED:20221118T091419Z
UID:6848-1654077600-1654084800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: Cristina Sarasa Buisán
DESCRIPTION:Seminar 2: FurC/PerR de Anabaena sp. PCC7120\, un regulador transcripcional que integra dos niveles de respuesta al estrés oxidativo. CRISTINA SARASA BUISÁN \ncristina-sarasa-buisan_v4_a4 \nWednesday\, 1 June 2022\n10:00 h\nAula del Edificio I+D
URL:https://bifi.es/schedule/i-ciclo-de-seminarios-jovenes-investigadores-area-bio-cristina-sarasa-buisan/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20220526
DTEND;VALUE=DATE:20220528
DTSTAMP:20260423T003119
CREATED:20220615T065125Z
LAST-MODIFIED:20220615T065125Z
UID:6882-1653523200-1653695999@bifi.es
SUMMARY:Congreso virtual "Géneros Digitales y Ciencia Abierta"
DESCRIPTION:Los días 26 y 27 de mayo se celebrará el Congreso virtual “Géneros Digitales y Ciencia Abierta”. Este congreso es una de las actividades realizadas en el marco del proyecto de investigación PID2019-105655RB-I00 (IIPP María José Luzón Y Carmen Pérez-Llantada). En el congreso se debatirá sobre el impacto de los rápidos desarrollos tecnológicos de la Web 2.0 y el fomento de la ciencia en abierto en las actuales prácticas de comunicación y difusión de la ciencia. \nIntervendrán como conferenciantes plenarios: \nProf. Vijay Bhatia (The Chinese University of Hong Kong)\nProf. Christoph Hafner (City University of Hong Kong)\nProf. Benedikt Fecher (Alexander von Humboldt Institute for Internet and\nSociety)\nProf. Emeritus John M. Swales (University of Michigan\, US) \nMás información sobre el congreso: http://genci.unizar.es/conference/ \nInscripción (gratuita) en la siguiente dirección:\nhttp://genci.unizar.es/conference/
URL:https://bifi.es/schedule/congreso-virtual-generos-digitales-y-ciencia-abierta/
LOCATION:Online
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220513T160000
DTEND;TZID=Europe/Madrid:20220513T180000
DTSTAMP:20260423T003119
CREATED:20220610T111418Z
LAST-MODIFIED:20221118T091455Z
UID:6842-1652457600-1652464800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: Helena García Cebollada
DESCRIPTION:Seminar 1: Protposer: a web server for rational stabilization of proteins. HELENA GARCÍA CEBOLLADA \nseminariohelenagarcia_panoramica-2\nFriday 13 May 2022\n16:00 horas\nSalón de actos del Edificio I+D\n¡¡Followed by Happy hour!!
URL:https://bifi.es/schedule/i-ciclo-de-seminarios-jovenes-investigadores-area-bio-helena-garcia-cebollada/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220404T083000
DTEND;TZID=Europe/Madrid:20220404T150000
DTSTAMP:20260423T003119
CREATED:20220330T072604Z
LAST-MODIFIED:20220330T072604Z
UID:6784-1649061000-1649084400@bifi.es
SUMMARY:Jornada de Bioingeniería y Biotecnología
DESCRIPTION:El próximo lunes 4 de abril se celebrará la Jornada de Bioingeniería y Biotecnología\, organizada por los Institutos Universitarios de Investigación (IUIs) de la Universidad de Zaragoza. \nEl encuentro acomete un doble objetivo: \n1) difundir e intercambiar el significativo conocimiento que se genera en la investigación de los institutos en el ámbito de la bioingeniería y biotecnología; \n2) generar nuevas colaboraciones multidisciplinares entre distintos grupos con experiencia y capacidades diferentes. \nLa jornada se celebrará en el Salón de Actos del Edificio I+D del Campus Río Ebro y se podrá seguir presencialmente u online\, registrándose previamente en el siguiente enlace Zoom: \nhttps://zoom.us/webinar/register/WN_gYFdy2gDTcKK2U1LgIib6A (tras la inscripción\, se recibirá un correo electrónico de confirmación con información para unirse al seminario web). \nEl programa de la Jornada puede consultarse jornada-bioingeniera-y-biotecnologa_20200404
URL:https://bifi.es/schedule/jornada-de-bioingenieria-y-biotecnologia/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220222T103000
DTEND;TZID=Europe/Madrid:20220222T120000
DTSTAMP:20260423T003119
CREATED:20220216T090722Z
LAST-MODIFIED:20220217T110408Z
UID:6724-1645525800-1645531200@bifi.es
SUMMARY:CIENCIA DIGITAL: SOSTENIBLE\, TRANSFORMATIVA Y TRANSVERSAL. RETOS Y PROSPECTIVA
DESCRIPTION:CIENCIA DIGITAL: SOSTENIBLE\, TRANSFORMATIVA Y TRANSVERSAL. RETOS Y PROSPECTIVA  \nprograma-ciencia-digital_webinar_22-feb-2022_c \nMartes 22/02/2022\nHora: 10.30-12.00h\nZoom webinar: https://zoom.us/j/92996415947
URL:https://bifi.es/schedule/ciencia-digital-sostenible-transformativa-y-transversal-retos-y-prospectiva/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20211203T123000
DTEND;TZID=Europe/Madrid:20211203T143000
DTSTAMP:20260423T003119
CREATED:20211115T100802Z
LAST-MODIFIED:20220124T135315Z
UID:6614-1638534600-1638541800@bifi.es
SUMMARY:BIFI TALK: Dr. Juan Luis Asensio (Instituto de Química Orgánica General\, CSIC\, Madrid)
DESCRIPTION:Title: Glycochemistry and Molecular Recognition: Rational and Combinatorial Approaches \nAbstract: \nCarbohydrates participate in a large variety of molecular recognition processes of biological relevance\, involving both proteins receptors\, enzymes and nucleic acid fragments. Understanding how these later bio-molecules interact with glycosides represents a fundamental issue in chemical biology with far reaching implications in fundamental biology\, biotechnology or drug design. On the other hand\, the acknowledgment of the relevance of glycoconjugates in biology has run parallel to the development of new chemical methods for glycosidic bond formation. Thus\, the last few decades have witnessed a burgeoning progress in the area of glycosyl donor engineering\, with a more recent focus on the understanding of glycosylation mechanisms. As a part of an ongoing project focused on glycochemisty we\nhave analyzed different aspects of the association of glycosides to both nulcleic acids and proteins. In addition\, key mechanistic features of glycosylation reactions\, both in enzymatic nd chemical contexts\, have been dissected. From a methodological persepective our approach is pluridisciplinar and includes NMR\, molecular modeling\, organic synthesis\, and a variety of chemical strategies. The obtained results\, together with their implications for the design and synthesis of improved carbohydrate-based ligands\, will be discussed. \njuan-l-asensio_bifitalks2021 \nFRIDAY\, 3rd DECEMBER 2021\, 12:30\nONLINE: ZOOM Seminar\nLink https://us02web.zoom.us/j/86384158190
URL:https://bifi.es/schedule/dr-juan-luis-asensio-instituto-de-quimica-organica-general-csic-madrid/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20211112T120000
DTEND;TZID=Europe/Madrid:20211112T140000
DTSTAMP:20260423T003119
CREATED:20211108T090509Z
LAST-MODIFIED:20211108T090509Z
UID:6589-1636718400-1636725600@bifi.es
SUMMARY:BIFI TALK: Dr. Jordi Soriano-Fradera (UBICS\, Universitat de Barcelona)
DESCRIPTION:Title: Approaches from physics of complex systems to model the brain in vitro \nAbstract \nNeuroengineering is one of the most exciting techniques in modern neuroscience. The capacity to design controlled environments for the neurons to grow and interconnect is opening new frontiers for the development of accurate in vitro systems that reproduce complex brain functions. In this talk\, I will present relatively simple yet\nsurprisingly enlightening experimental designs that are analyzed in the context of dynamical systems and complex networks. The experiments\, and the analytical toolboxes that we derived\, are helping us to better understand the intricate relationship between connectivity and dynamics in living neuronal networks\, and are opening new avenues for the treatment of neurological disorders. \njordi_soriano_bifitalks2021 \nBIFI-Talks 2021\n12 NOVEMBER 12:00 pm\nONLINE: ZOOM Seminar\nLink: https://us02web.zoom.us/j/88242666124
URL:https://bifi.es/schedule/bifi-talk-dr-jordi-soriano-fradera-ubics-universitat-de-barcelona/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20211008T120000
DTEND;TZID=Europe/Madrid:20211008T143000
DTSTAMP:20260423T003119
CREATED:20211001T103324Z
LAST-MODIFIED:20211001T105748Z
UID:6475-1633694400-1633703400@bifi.es
SUMMARY:BIFI TALK: Dra. Cintia Roodveldt (investigadora Ramón y Cajal. Universidad de Sevilla)
DESCRIPTION:Title: Neurodegenerative proteinopathies: implications and molecular mechanisms of MOK signaling kinase in neuroinflammatory responses. \nAbstract: \nNeurodegenerative diseases\, including Alzheimer’s\, Parkinson’s and Amyotrophic lateral sclerosis (ALS) are incurable proteinopathies characterized by progressive neuronal loss\, aggregation and deposition of specific proteins in the central nervous system (CNS) and sustained neuroinflammation. In the last few years\, it has become increasingly accepted that such protein aggregates have a principal role in triggering neurotoxic immune responses. Still\, and particularly for ALS\, the molecular mechanisms and proteins participating in these pathogenic processes remain largely unknown. Recently\, we have identified MOK Ser/Thr kinase as a TDP-43-interacting protein in an ALS microglial cell model (Leal-Lasarte et al.\, FASEB J. 2017). Our recent studies\, involving biochemical\, transcriptomic and interactomic approaches\, shed light on the role and molecular mechanisms of MOK in dysregulated immune responses in ALS and other related diseases. \ncintia-roodveldt_bifitalks2021 \nFRIDAY\, 8th OCTOBER 2021\, 12:00\nONLINE: ZOOM Seminar\nLink: https://us02web.zoom.us/j/85809480012 \n 
URL:https://bifi.es/schedule/bifi-talk-dra-cintia-roodveldt-investigadora-ramon-y-cajal-universidad-de-sevilla/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210604T123000
DTEND;TZID=Europe/Madrid:20210604T143000
DTSTAMP:20260423T003119
CREATED:20210527T061633Z
LAST-MODIFIED:20210527T061633Z
UID:6440-1622809800-1622817000@bifi.es
SUMMARY:BIFI TALK: Dr. Sandro Meloni (CSIC-UIB)
DESCRIPTION:Title: Ecology of Online Social Systems \nAbstract \nOnline social networks have significantly changed global communication dynamics and\, in general\, the way we interact. Every day our brain is flooded by information coming from a plethora of sources and this cognitive bottleneck translates into hyper-competition for a scarce resource: our attention. This pressure\, in turn\, pushes information producers to mutualistically interact with specific memes and actors\, seeking the virality of their messages. Finally\, memes’ chances to persist and spread are subject to changes in the communication environment. The fact that all these terms — competition for resources\, mutualism and environmental changes– are\nreminiscent of another research field –ecology–\, suggests that\, at least at a coarse-grained level\, “information” ecosystems and natural ecosystems present strong similarities that can be exploited to understand their behavior.\nIn this talk\, building on these analogies\, I will show how theories and tools developed for the study of ecological communities help to gain insights on human behavior in online social interactions. In the first part\, I will introduce an analytical formalism –based on the neutral theory of ecology–\, capable of capturing the competition for attention and explaining several emergent patterns observed in information ecosystems. In the second part\, using both\ndata analysis and numerical modeling\, I will focus on the structure of information ecosystems showing that the underlying architecture of empirical actor-meme networks evolves towards self-similar nested arrangements like the ones found in natural mutualistic assemblages. \nmeloni_bifitalks2021 \nDIA Y HORA: 4 DE JUNIO A LAS 12:30\nONLINE: ZOOM Seminar\nSeminar Link: https://us02web.zoom.us/j/88679866793
URL:https://bifi.es/schedule/bifi-talk-dr-sandro-meloni-csic-uib/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210528T120000
DTEND;TZID=Europe/Madrid:20210528T140000
DTSTAMP:20260423T003119
CREATED:20210524T094204Z
LAST-MODIFIED:20210524T094333Z
UID:6435-1622203200-1622210400@bifi.es
SUMMARY:Conferencia invitada. Francisco Castejón (Consejo de Seguridad Nuclear)
DESCRIPTION:Transformando el Consejo de Seguridad Nuclear para mejorar la seguridad nuclear y la protección radiológica. \nEl papel del Consejo de Seguridad Nuclear (CSN) en el contexto de la situación actual será el tema central de la conferencia. La renovación en la que se encuentra inmerso dicho organismo pretende aportar mas transparencia con el fin de generar mas confianza y seguridad en la sociedad. En este sentido la ciencia ciudadana podría jugar un papel importante. \nDia: 28 de Mayo 2021\,\nHora: 12 h\nLugar: Aula Magna del Paraninfo de la Universidad de Zaragoza. Edificio Paraninfo.\nPlaza de Paraíso 4. Zaragoza
URL:https://bifi.es/schedule/conferencia-invitada-francisco-castejon-consejo-de-seguridad-nuclear/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210507T123000
DTEND;TZID=Europe/Madrid:20210507T150000
DTSTAMP:20260423T003119
CREATED:20210426T125923Z
LAST-MODIFIED:20210426T130036Z
UID:6414-1620390600-1620399600@bifi.es
SUMMARY:BIFI TALK: Prof. Nuria Verdaguer (IBMB-CSIC\, Barcelona)
DESCRIPTION:Title: From structure to mechanisms of Zika virus induced neurodevelopmental disease \nAbstract:\nZika virus (ZIKV) infection was declared a global threat for public health due to its association with congenital neurodevelopmental birth defects\, such as microcephaly\, a rare medical condition characterized by a significant decrease in brain size. ZIKV infection delays cell cycle progression and induces cell death of neural progenitor cells (NPCs)\, leading to reduced production of neurons. Despite the enormous basic and clinical research efforts\, no specific therapy has yet been approved for the treatment or prevention of ZIKV infection\, thus a better understanding of its pathogenesis is an urgent need.\nOur recent studies of the effect of ZIKV proteins on NPC proliferation show that the protein NS5 that is essential for viral genome replication\, is also sufficient to alter the mode of division of NPCs. NS5 interacts and depletes primary cilia and centrosome components\, causing an atypical non-genetic ciliopathy and premature neuron delamination. While the Methyltransferase (MTase) and RNAdependent RNA polymerase (RdRP) activities of ZIKV-NS5\nappear to be dispensable\, the Y25\, K28 and K29 residues that are involved in NS5 oligomerization\, are essential for the localization and interactions with proteins of the cilia base\, promoting ciliopathy and premature neurogenesis. In\nthis talk I will summarize our recent findings\, exploring these unexpected interactions between ZIKV-NS5 and different cilia/centrosome proteins. These data will shed new light into the mechanisms by which NS5 interferes with the molecular machinery of primary cilia formation\, highlighting new potential targets for therapeutic intervention. \nnuria-verdaguer_bifitalks2021 \nBIFI-Talks 2021\nDIA Y HORA: 7 DE MAYO A LAS 12:30\nONLINE: ZOOM Seminar\nLink: https://us02web.zoom.us/j/83011713089
URL:https://bifi.es/schedule/bifi-talk-prof-nuria-verdaguer-ibmb-csic-barcelona/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210416T123000
DTEND;TZID=Europe/Madrid:20210416T153000
DTSTAMP:20260423T003119
CREATED:20210409T113523Z
LAST-MODIFIED:20210409T120746Z
UID:6384-1618576200-1618587000@bifi.es
SUMMARY:BIFI TALK Dr. Ernesto Estrada (ARAID-IUMA-Universidad de Zaragoza)
DESCRIPTION:Tittle: Networks Virology. Learning from SARS-CoV-2 \nAbstract: \nViruses are reproductive machineries formed mainly by genetic material (RNA or DNA) and proteins. In general\, these proteins interact with specific proteins of the host forming vast networks of virus-host protein-protein interactions (PPI). Although a virus may infect mainly an organ or system of the host\, the damages can propagate beyond it\, transforming the affection into a multiorganic/multifunctional one. This is the case of SARS-CoV-2\, which makes COVID-19 a multiorganic disease affecting a dozen of organs/systems in humans. Here\, I develop the hypothesis based on facts that this propagation of extrapulmonary damages takes place via the PPI network of virus-host interactions. It considers that some viral proteins interact with specific human proteins highly expressed in the lungs. Then\, these perturbed human proteins navigate outside the lungs via an exosome-mediated transport network\, which allows the inter-organ cross-talk. Due to the fact that these “perturbated” proteins interact with their partners in other organs they are capable to transmit such perturbations beyond the lungs. Therefore\, there is a network of perturbators from the lungs interacting with a network of vulnerable proteins in other organs\, which trigger a range of damages in them. We identify here the perturbators and vulnerable proteins in COVID-19\, identifying 13 organs/systems that may be affected by the infection of SARS-CoV-2 and explain some of the extrapulmonary damages observed in clinics. We propose a series of drugs that can be repurposed to treat combinations of these damages in COVID-19 patients. Finally\, at a lower size-scale we zoom on these SARS-CoV-2 proteins to investigate their topological structure\, which form other networks of amino-acids interacting noncovalently among them. Using these techniques\, we are able to identify weak pints in such proteins that can be used as pharmacological targets. \nestrada_bifitalks2021 \n16 APRIL 12:30\nONLINE: WEBINAR ZOOM\nLink: https://us02web.zoom.us/j/84993664074
URL:https://bifi.es/schedule/bifi-talk-dr-ernesto-estrada/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210319T123000
DTEND;TZID=Europe/Madrid:20210319T140000
DTSTAMP:20260423T003119
CREATED:20210224T075819Z
LAST-MODIFIED:20210315T075448Z
UID:6163-1616157000-1616162400@bifi.es
SUMMARY:BIFI TALK. Dr. Enrique Marcos (IBMB-CSIC\, Barcelona)
DESCRIPTION:Title: De novo protein design for tailoring structure and function \nSpeaker: Dr. Enrique Marcos (IBMB-CSIC\, Barcelona) \nAbstract: \nThe recent revolution of de novo protein design is transforming the protein engineering field. Instead of searching and modifying natural proteins\, de novo protein design crafts new proteins from physical principles with sequences and geometries not restricted to those seen in nature. From scratch\, protein backbones are computationally generated according to geometrical\nrestrictions defined by the designer\, followed by the calculation of low-energy amino acid sequences stabilizing these backbones. In this way\, protein\nstructures are tailored for stability and function; potentially overcoming frequent limitations of repurposed natural proteins in terms of stability\, geometry\, size\, recombinant expression or protein interactions\, among others. We have identified key principles for the de novo design of a variety of protein folds containing beta-sheets\, which are attractive structural motifs for building ligand-binding sites\, and used these principles for computationally designing proteins in excellent agreement with their experimental structures. This has opened the door to custom-design proteins for binding small-molecules and protein targets of therapeutic relevance. De novo proteins allow us to explore a vast sequence and structural space to develop novel biotechnological\nsolutions\, and ultimately advance our understanding on how proteins work. \nenrique-marcos_bifitalks2021 \nDIA Y HORA: 19 DE MARZO A LAS 12:30\nONLINE: Meeting ZOOM\nLink: https://us02web.zoom.us/j/85377863712
URL:https://bifi.es/schedule/bifi-talk-dr-enrique-marcos-ibmb-csic-barcelona/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20210203
DTEND;VALUE=DATE:20210206
DTSTAMP:20260423T003119
CREATED:20210102T195457Z
LAST-MODIFIED:20210102T195703Z
UID:6075-1612310400-1612569599@bifi.es
SUMMARY:X National Conference BIFI 2021
DESCRIPTION:The X National Conference BIFI 2021 (http://bifi21.bifi.es) of the Institute for Biocomputation and Physics of Complex Systems  (BIFI) aims at giving all participants the chance to disseminate their work\, and at the same time strengthening existing collaborations or establishing new ones within the different research lines promoted by the BIFI. \nThe format of the congress will include plenary sessions\, with invited and contributed talks\, as well as the corresponding poster sessions. \nMAIN TRACKS: \n\nBiochemistry\, Molecular and Cellular Biology\nPhysics\nBiophysics\nComputation\n\nCALL FOR COMMUNICATIONS \nResearchers from any Institution are warmly invited to attend the meeting\, and submit scientific communications related to the Main Tracks of the event. We could limit the attendees number due to a capacity issue at the conference rooms\, so that\, if necessary\, we might reject applications to participate. \nIMPORTANT DATES \nDates of the Conference: February 3 – February 5\, 2021 \nRegistration deadline: January 31st 2021\nAbstract submission deadline: January 8 th\, 2021\nNotification to authors: not later than January 15th\, 2021 \nVENUE \nZoom I+D Room
URL:https://bifi.es/schedule/x-national-conference-bifi-2021/
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200228T080000
DTEND;TZID=Europe/Madrid:20200229T170000
DTSTAMP:20260423T003119
CREATED:20200108T122810Z
LAST-MODIFIED:20200109T142717Z
UID:5436-1582876800-1582995600@bifi.es
SUMMARY:CURSO DE INVIERNO DE LA UNIVERSIDAD DE ZARAGOZA Nuevas perspectivas en la evolución de los genes y proteínas / Advances in Genome and Protein Evolution 28-29 de Febrero en Jaca (Huesca)
DESCRIPTION:Abierta la Inscripción del CURSO DE INVIERNO DE LA UNIVERSIDAD DE ZARAGOZA Nuevas perspectivas en la evolución de los genes y proteínas / Advances in Genome and Protein Evolution 28-29 de Febrero en Jaca (Huesca)  en https://cursosextraordinarios.unizar.es/cursos-invierno \nLas personas interesadas en pedir una ayuda económica para asistir a dicho curso deben inscribirse ahora pero NO pagar la matrícula de momento.  Para solicitar la ayuda deberán escribir a i.yruela@csic.es y mmartine@unizar.es adjuntado un breve CV. El plazo límite para pedir esta ayuda es el 28 de Enero de 2020. \nINFORMACIÓN CURSO\nDirección: Inmaculada Yruela y Marta Martínez Júlvez \nPonentes y sesiones: \nPilar Catalán\, Universidad de Zaragoza    \n-Phylogenetic concepts. Organismal phylogenetic reconstruction and evolutionary speciation events\n-Phylogenetic methods. From distance-based methods to the coalescent approach\n\nInmaculada Yruela\, CSIC\, Zaragoza \n-Introduction to sequence analysis and protein phylogeny \nToni Gabaldón\, Supercomputing Centre (BSC-CNS) and Institute for Research in Biomedicine (IRB)\, Barcelona\n-Homology\, orthology and paralogy\n-Comparative genomics and phylogenomics\n\nUgo Bastolla\, Centro de Biología Molecular Severo Ochoa (UAM-CSIC)\, Madrid\n–Detecting selection on protein structure and protein folding stability\n-Substitution processes with selection on protein structure and protein folding stability \nLeandro Radutsky\, Centro de Regulación Genómica (CRG)\, Barcelona\n-Structural bioinformatics for the analysis of protein mutations with focus on disease and evolution \nDirigido a: Estudiantes de los últimos cursos de los grados en Química\, Biología\, Física\, Farmacia\, Medicina\, Bioquímica\, Biotecnología\, Veterinaria. Estudiantes de másteres de Química Molecular\, Bioquímica\, Biología Molecular y Celular\, Biomedicina\, Biotecnología. Estudiantes de doctorado. Profesionales en activo en cualquiera de las áreas de conocimiento y especialidades anteriormente enumeradas. \nEste curso tiene reconocidos 0\,5 ECTS como Formación Permanente de Profesorado
URL:https://bifi.es/schedule/curso-de-invierno-de-la-universidad-de-zaragoza-nuevas-perspectivas-en-la-evolucion-de-los-genes-y-proteinas-advances-in-genome-and-protein-evolution-28-29-de-febrero-en-jaca-huesca/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200210T123000
DTEND;TZID=Europe/Madrid:20200210T123000
DTSTAMP:20260423T003119
CREATED:20200128T095106Z
LAST-MODIFIED:20200128T095136Z
UID:5494-1581337800-1581337800@bifi.es
SUMMARY:BIFI TALK. Fabio Dercole
DESCRIPTION:Title: Direct reciprocity and model-predictive strategy update explain the network reciprocity observed in socio-economic networks \nSpeaker: Fabio Dercole \nAbstract:\nNetwork reciprocity has been successfully put forward (since M.A. Nowak & R. May’s\, 1992\, influential paper) as the simplest mechanism — requiring no strategical complexity — supporting the evolution of cooperation in biological and socio-economic systems. The mechanism is actually the network\, that makes agents’ interactions localized\, while network reciprocity is the property of the underlying evolutionary process of favoring cooperation in sparse rather than dense networks. In theoretical models\, the property holds under imitative evolutionary processes\, that however lack rationality in the socio-economic context\, whereas cooperation disappears in any network if imitation is replaced by the more rational best-response rule of strategy update. In social experiments\, network reciprocity has been observed\, though the imitative behavior did not emerge. What did emerge is a form of conditional cooperation based on direct reciprocity—the propensity to cooperate with neighbors who previously cooperated. To resolve this inconsistency\, we show network reciprocity in a model that\nrationally confronts the two main behaviors emerging in experiments — reciprocal cooperation and unconditional defection — with rationality introduced by means of a multi-step model-predictive rule for strategy update. \nSala de Conferencias\, Edif. I+D\, Campus Rio Ebro\nLUNES 10 de FEBRERO a las 12:30h
URL:https://bifi.es/schedule/bifi-talk-fabio-dercole/
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200203T110000
DTEND;TZID=Europe/Madrid:20200205T130000
DTSTAMP:20260423T003119
CREATED:20191029T110631Z
LAST-MODIFIED:20191029T110822Z
UID:5368-1580727600-1580907600@bifi.es
SUMMARY:IX International BIFI 2020 Conference
DESCRIPTION:La IX Conferencia Internacional BIFI 2020 tendrá lugar en Zaragoza\, en el salón de actos del Edificio I+D\, Campus Río Ebro (Actur)\, del 3 al 5 de febrero del año próximo 2020. \nEn esta ocasión (la conferencia) está enfocada en “Nuevos retos en Biotecnología Molecular (New Challenges in Molecular Biotechnology). Así\, hemos preparado un programa científico con oradores invitados nacionales e internacionales que creemos que es muy atractivo. El formato del evento incluye sesiones plenarias con 18 charlas\, 5 de las cuales serán impartidas por prominentes investigadores que realizan su investigación en reconocidos centros como el Instituto Pasteur de Paris\, la Unidad de Biología Mitocondrial de Cambridge\, la Estación Experimental de Aula Dei (CSIC) de Zaragoza\, el Instituto Rocasolano de Madrid\, y el Laboratorio de Sistemas Bioquímicos (CIB-CSIC)\, también de Madrid. Nueve de los trabajos inscritos serán elegidos para impartir charlas cortas de 12 min (+3 de preguntas) y se han programado dos sesiones para la presentación de pósters de los cuales serán premiados dos con las cantidades de 300€ (Primer premio) y 200€ (Segundo premio). \nInvitamos cordialmente a los investigadores jóvenes y a aquellos no tan jóvenes\, también a estudiantes\, a asistir a esta nueva edición de nuestra Conferencia bienual y a enviar comunicaciones científicas relacionadas con los temas principales del evento. Queremos en este marco brindaros la oportunidad de difundir vuestro trabajo y de poder crear y/o fortalecer nuevas colaboraciones científicas. \nLos plazos de inscripción son: 20 de diciembre (Early) y 10 de enero (Late)\, con diferentes importes de las cuotas de inscripción (vea las diferentes opciones en el sitio del evento). La notificación por parte del Comité Organizador a aquellos cuyos trabajos resultasen elegidos para impartir charlas cortas se realizará como muy tarde el día 17 de enero de 2020. \nEn el sitio web del evento (http://bifi20.bifi.es/) podrás encontrar toda la información necesaria para inscribirte\, así como el Programa Científico\, elementos importantes sobre nuestro Instituto (el lugar de celebración de la Conferencia)\, la ciudad de Zaragoza y más. \nSi estás interesado/a en asistir\, por favor regístrate cuanto antes.\nDesde ya os damos la bienvenida en Zaragoza. \nEl Comité Organizador
URL:https://bifi.es/schedule/ix-international-bifi-2020-conference/
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200203T100000
DTEND;TZID=Europe/Madrid:20200205T130000
DTSTAMP:20260423T003119
CREATED:20191029T111444Z
LAST-MODIFIED:20191029T111631Z
UID:5375-1580724000-1580907600@bifi.es
SUMMARY:IX International BIFI 2020 Conference
DESCRIPTION:The IX International BIFI 2020 Conference will take place in Zaragoza\, in the auditorium of the R+D Building\, Río Ebro Campus (Actur)\, from February 3rd to 5th\, 2020. \nOn this occasion the Conference will be focused on “New Challenges in Molecular Biotechnology“. Thus\, we have prepared a scientific program with national and international speakers that we believe is very attractive. The event format includes plenary sessions with 18 talks by invited speakers\, 5 of which will be given by prominent researchers who conduct their research in renowned research centers such as the Pasteur Institute in Paris\, the Mitochondrial Biology Unit in Cambridge\, the Estación Experimental de Aula Dei (CSIC ) in Zaragoza\, the Rocasolano Institute in Madrid\, and the Laboratory of Systems Biochemistry (CIB-CSIC) also in Madrid. In addition\, nine of the works submitted will be chosen to give short oral talks of 12 min (+3 question-minutes). Two Poster sessions have been scheduled from which two works presented in this modality will be awarded with the amounts of €300 (First prize) and €200 (Second prize). \nWe warmly invite young and not so young researchers\, and also students\, to attend this new edition of our biennial conference and to send scientific communications related to the main tracks of the event. Our main purpose is giving you the opportunity to communicate your research and to create and/or strengthen new scientific collaborations. \nRegistration deadlines will be December 20th (Early) and January 10th (Late)\, with different registration fees in each case (see the different options on the event site). Notification by the Organizing Committee to those whose works were chosen to give short oral talks will be made at the latest on January 17th\, 2020. \nOn the website of the event (http://bifi20.bifi.es/) you will find all the necessary information to register\, also the Scientific Program\, as well as important aspects about the BIFI Institute (the venue of the Conference)\, the city of Zaragoza\, and more. \nIf you are interested in attending\, please register as soon as possible. \nWe welcome you in Zaragoza.
URL:https://bifi.es/schedule/ix-international-bifi-2020-conference-2/
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20191213T123000
DTEND;TZID=Europe/Madrid:20191213T140000
DTSTAMP:20260423T003119
CREATED:20190310T193842Z
LAST-MODIFIED:20191212T093515Z
UID:5164-1576240200-1576245600@bifi.es
SUMMARY:BIFI TALK - Javier Oroz
DESCRIPTION:Título: Structural biology in human disease: What can we learn from the study of disordered proteins?\n \nPonente: Javier Oroz (IQFRS-CSIC\, Madrid) \nDía y hora:  13 de diciembre a las 12.30 \nLugar: SALA DE CONFERENCIAS\, EDIFICIO I+D+i\, CAMPUS RIO EBRO
URL:https://bifi.es/schedule/bifi-talk-javier-oroz/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20191108T123000
DTEND;TZID=Europe/Madrid:20191108T140000
DTSTAMP:20260423T003119
CREATED:20190310T193558Z
LAST-MODIFIED:20191212T093332Z
UID:5160-1573216200-1573221600@bifi.es
SUMMARY:BIFI TALK - Javier Galeano
DESCRIPTION:Título: A quick review of ecology of bacteriaA quick review of ecology of bacteria  \nPonente: Javier Galeano (UPM\, Madrid) \nDía y hora:  8 de noviembre a las 12.30 \nLugar: SALA DE CONFERENCIAS\, EDIFICIO I+D+i\, CAMPUS RIO EBRO
URL:https://bifi.es/schedule/bifi-talk-javier-galeano/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20191004T130000
DTEND;TZID=Europe/Madrid:20191004T140000
DTSTAMP:20260423T003119
CREATED:20190310T193037Z
LAST-MODIFIED:20190917T070838Z
UID:5157-1570194000-1570197600@bifi.es
SUMMARY:BIFI TALK - Javier García-Nafría
DESCRIPTION:Título: Cryo-electron microscopy: moving beyond X-ray crystallography for membrane receptors and drug discovery\n \nPonente: Javier García-Nafría (LMB/MRC\, Cambridge\, UK-University of Zaragoza) \nDía y hora:  4 de octubre a las 13:00 h \nLugar: SALA DE CONFERENCIAS\, EDIFICIO I+D+i\, CAMPUS RIO EBRO \nResumen: \nCryo-electron microscopy (cryo-EM) has undergone major advances during the last years\, with special impact in structural biology of membrane proteins. I will review the advances in cryo-EM technology that made the ¨resolution revolution¨ possible\, and then show its application to understand G-protein coupled receptors (GPCRs). GPCRs are the largest family of membrane proteins in the human body and are a target for ~35% of the currently approved FDA drugs. GPCRs sense a variety of molecules and transduce the signal to the intracellular milieu by coupling to heterotrimeric G-proteins. We used cryo-EM to obtain high-resolution structural information on GPCR-G protein complexes\, starting to tackle one of the major questions in the field – the GPCR-G protein selectivity code. I will then analyse the state-of-the-art in using cryo-EM for structure-based drug discovery of membrane proteins. \nReferences: \n\nCryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein. García-Nafría J.*\, Lee Y.*\, Bai X.\, Carpenter B. & Tate CG. 2018. Elife. May 4;7. pii: e35946.\n\n\nCryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go. García-Nafría J.\, Nehme R.\, Edwards P.\, Tate CG. 2018. Nature 558 (7711). 620-62\n\n\nCryo-EM structures of GPCRs coupled to Gs\, Gi and Go.  García-Nafría J. and Tate CG. Molecular and Cellular Endocrinology. 2019\, In press.\n\n\nCryo-Electron Microscopy: Moving Beyond X-ray Crystal Structures for Drug receptors and Drug development. García-Nafría J. and Tate CG. 2019. Annual Reviews in Pharmacology and Toxicology. 2020. In press (2019 Jul 26. doi: 10.1146.)\n\n\n 
URL:https://bifi.es/schedule/bifi-talk-javier-garcia-nafria/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20190607T123000
DTEND;TZID=Europe/Madrid:20190607T140000
DTSTAMP:20260423T003119
CREATED:20190310T192426Z
LAST-MODIFIED:20190310T192632Z
UID:5153-1559910600-1559916000@bifi.es
SUMMARY:BIFI TALK - Joaquín Marro
DESCRIPTION:Título: Por confirmar \nPonente: Joaquín Marro \nDía y hora:  7 de junio a las 12.30 \nLugar: SALA DE CONFERENCIAS\, EDIFICIO I+D+i\, CAMPUS RIO EBRO
URL:https://bifi.es/schedule/bifi-talk-joaquin-marro/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20190510T123000
DTEND;TZID=Europe/Madrid:20190510T140000
DTSTAMP:20260423T003119
CREATED:20190310T191939Z
LAST-MODIFIED:20190310T192021Z
UID:5149-1557491400-1557496800@bifi.es
SUMMARY:BIFI TALK - Mónica Balsera
DESCRIPTION:Título: Por confirmar \nPonente: Mónica Balsera (IRNASA -CSIC\, Salamanca) \nDía y hora:  10 de Mayo a las 12.30 \nLugar: Aula\, EDIFICIO I+D+i\, CAMPUS RIO EBRO
URL:https://bifi.es/schedule/5149/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
END:VCALENDAR