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X-WR-CALNAME:BIFI -  - Institute for Biocomputation and Physics of Complex Systems
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X-WR-CALDESC:Events for BIFI -  - Institute for Biocomputation and Physics of Complex Systems
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240621T120000
DTEND;TZID=Europe/Madrid:20240621T140000
DTSTAMP:20260422T022413
CREATED:20240612T090042Z
LAST-MODIFIED:20240912T081746Z
UID:8124-1718971200-1718978400@bifi.es
SUMMARY:BIFI-Talk: Sara García Linares. Universidad Complutense de Madrid.
DESCRIPTION:BIFI–Talk: Sara García Linares. Universidad Complutense de Madrid. \nTitle: Design of nanoreactors for plastic depolymerization based on pore-forming toxins \nAbstract\nPetroleum-based plastics are durable and accumulate in all ecological niches. Approximately 80% of waste objects are made of macroplastics\, with most ending up dumped into the oceans. PET (polyethylene terephthalate) is the primary component in many synthetic fibers and water bottles\, comprising 14.4% of total plastic waste. Our work focuses on improving biotechnological processes for PET degradation by designing more efficient enzymes. To achieve this\, we design biocatalytic nanopores using computational modeling\, based on the homo-octamer of a sea anemone toxin that forms pores in biological membranes. These pores are assembled into nanodiscs\, forming individual water-soluble particles. At a temperature of only 40 °C and neutral pH\, this biocatalytic nanoreactor can degrade PET nanoparticles from plastic bottles and other commercial versions of PET used in manufacturing plastic products. The products of these reactions include soluble BHET dimer\, BHET itself\, and mono-(2-hydroxyethyl)-terephthalic acid (MHET). The results obtained so far constitute a proof-of-concept for building biodegradable pore-based catalytic nanoreactors that could drive new developments in nanobiotechnology. This is exemplified by efficient systems for decomposing PET at levels comparable to the best-performing known engineering PETases\, and moreover\, at relatively low temperatures. \nReferences\nA. Robles-Martín\, R. Amigot-Sánchez\, S. Roda\, […]\, S. García-Linares*\, M. Ferrer*\, V. Guallar* (2023). “Sub-micro- and nano-sized polyethylene terephthalate deconstruction with engineered protein nanopores”. Nature Catalysis 6\, 1174–1185. DOI: 10.1038/s41929-023-01048-6. \nFRIDAY\, 21st June 2024\, 12:00 h\nEdificio I+D (Conference room)
URL:https://bifi.es/schedule/bifi-talk-sara-garcia-linares-universidad-complutense-de-madrid/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240524T130000
DTEND;TZID=Europe/Madrid:20240524T150000
DTSTAMP:20260422T022413
CREATED:20240516T084936Z
LAST-MODIFIED:20240516T085043Z
UID:8098-1716555600-1716562800@bifi.es
SUMMARY:BIFI TALK: Athi N Naganathan\, Indian Institute of Technology Madras (IITM)\, Chennai\, India
DESCRIPTION:BIFI TALK: Athi N Naganathan\, Indian Institute of Technology Madras (IITM)\, Chennai\, India \nTitle:  Conformational Tuning as a Mechanism to Determine Specificity and\nPromiscuity \nAbstract: \nParalogous proteins confer enhanced fitness to organisms via complex sequence-conformation codes that shape functional divergence\, specialization\, or promiscuity. Here\, we resolve the underlying mechanism of promiscuous binding versus partial sub-functionalization by studying paralogous Acyl-CoA Binding Proteins (ACBPs) from Plasmodium falciparum. Combining experiments and simulations on two of the paralogs\, A16 and A749\, we show that minor sequence differences shape nearly every conformational feature. A749 displays a heterogeneous native ensemble\, weaker thermodynamic coupling\, enhanced fluctuations\, and a larger binding-pocket volume\, compared to A16. Tryptophan probes signal a graded reduction in the sampling of substates in the holo form\, hinting at conformational-selection-like mechanism of binding. They exhibit a spectrum of binding affinities to acyl-CoAs with A749\, the\nmore promiscuous and hence the likely ancestor\, binding 1000-fold stronger to Lauroyl-CoA. We thus demonstrate how minor differences in long-range coupling and dynamics contribute to the evolution of contrasting functional repertoires in paralogs. \n  \nFRIDAY\, 24th May 2024\, 13:00 h\nEdificio I+D (Aula room)
URL:https://bifi.es/schedule/bifi-talk-athi-n-naganathan-indian-institute-of-technology-madras-iitm-chennai-india/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240514T100000
DTEND;TZID=Europe/Madrid:20240514T130000
DTSTAMP:20260422T022413
CREATED:20240430T083311Z
LAST-MODIFIED:20240516T084426Z
UID:8094-1715680800-1715691600@bifi.es
SUMMARY:Webinar Digital Genres and Open Science
DESCRIPTION:M José Luzón and Carmen Pérez-Llantada (Digital Science Lab \nComputing and Data ScienceBIFI) cordially invite you to participate in the webinar “Digital Genres and Open Science”\, which will take place on Tuesday\, 14 May 2024\, from 10:00 to 13:00 (Madrid time). \nThe webinar will consist of three sessions dedicated to the presentation of our findings on digital genres for the promotion and dissemination of science. This presentation will be followed by a multidisciplinary round table (in Spanish): Oportunidades y retos de la comunicación digital) on the opportunities and challenges of open science. \nA member of BIFI (Olga Abián) and members of Fundación Ibercivis (Francisco Sanz and Daniel Lisbona) are some of the invited speakers in this round table! See the programme on our website (https://genci.unizar.es/dissemination-event/) \nThe webinar is aimed at linguists with an interest in digital genres and researchers who wish to disseminate their research on the web. To attend\, please complete the registration form here: https://docs.google.com/forms/d/e/1FAIpQLSelvvz006mRNM9F5HRVrnL2heR9vfRsu00M8Bk70qJV4L1ZLg/viewform
URL:https://bifi.es/schedule/webinar-digital-genres-and-open-science/
LOCATION:Online
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240508T123000
DTEND;TZID=Europe/Madrid:20240508T143000
DTSTAMP:20260422T022413
CREATED:20240430T082513Z
LAST-MODIFIED:20240516T083246Z
UID:8090-1715171400-1715178600@bifi.es
SUMMARY:BIFI TALK: Narimantas Cenas\, Vilnius University of Lituania
DESCRIPTION:BIFI TALK: Narimantas Cenas\, Vilnius University of Lituania \nTitle: Single- and two-electron reduction of nitroaromatic compounds by\nflavoenzymes: mechanisms and implications for cytotoxicity \nWednesday\, 8th May 2024\, 12:30 h\nEdificio I+D (Conference room)
URL:https://bifi.es/schedule/bifi-talk-narimantas-cenas-vilnius-university-of-lituania/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240322T123000
DTEND;TZID=Europe/Madrid:20240322T143000
DTSTAMP:20260422T022413
CREATED:20240308T060033Z
LAST-MODIFIED:20250314T105929Z
UID:8034-1711110600-1711117800@bifi.es
SUMMARY:Biophyzza Connection
DESCRIPTION:On March 22 at 12:30 a scientific dissemination event will take place at the Agri-Food Market at the San Francisco Campus (next to the campus pond\, C. Pedro Cerbuna\, 12) to give visibility to the BIOPHYSICS knowledge area. This day is part of the Biophysics Week (https://www.biophysics.org/biophysics-week#/) organized annually by the Biophysical Society of the United States with events around the world. \nThe event will consist of two informal talks by two researchers from the Institute of Biocomputation and Physics of Complex Systems (BIFI)\, one on toxic proteins involved in the development of neurodegenerative diseases\, given by Dr. Nunilo Cremades\, and another on drug Discovery using electron microscopy\, given by Dr. Javier García-Nafría. The talks will be enlivened with pizza. \nOur event will be held jointly with others at different Spanish universities coordinated by the Spanish Biophysics Society (SBE\, http://www.sbe.es/) in an activity called ‘The Biophyzza Connection’ with the sponsorship of Domino’s Pizza . \nIn addition\, the event is supported by the European project ivBM-4PAP (ivBM-4PAP is a research project funded by the European Innovation Council through its Horizon Europe Pathfinder programme with grant agreement No. 101098989)\, whose PI is Nunilo Cremades. \n  \nHope to see you there!!!
URL:https://bifi.es/schedule/biophyzza-connection/
LOCATION:Campus San Francisco de la Universidad de Zaragoza
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240207T100000
DTEND;TZID=Europe/Madrid:20240207T120000
DTSTAMP:20260422T022413
CREATED:20240124T073711Z
LAST-MODIFIED:20240124T073909Z
UID:7984-1707300000-1707307200@bifi.es
SUMMARY:III Cycle of young researcher seminars: Miguel Campos
DESCRIPTION:Miguel Campos\, Bioflora\, Escuela Politécnica Superior\, Huesca \nComparative and functional genomics: a comprehensive approach to understanding the evolution of the Brachypodium annualis complex \nWednesday\, 7 th February \, 10 h\nSala de conferencias. Edificio I+D\, Mariano Esquillor S/N. \n 
URL:https://bifi.es/schedule/ii-cycle-of-young-researcher-seminars-miguel-campos/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240117
DTEND;VALUE=DATE:20240120
DTSTAMP:20260422T022413
CREATED:20231016T095942Z
LAST-MODIFIED:20231016T095942Z
UID:7534-1705449600-1705708799@bifi.es
SUMMARY:XI International Conference BIFI 2024. ARTIFICIAL INTELLIGENCE AT THE CROSSROADS OF INTERDISCIPLINARY SCIENCE
DESCRIPTION:XI International Conference BIFI 2024.\nARTIFICIAL INTELLIGENCE AT THE CROSSROADS OF INTERDISCIPLINARY SCIENCE
URL:https://bifi.es/schedule/xi-international-conference-bifi-2024-artificial-intelligence-at-the-crossroads-of-interdisciplinary-science/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231201T100000
DTEND;TZID=Europe/Madrid:20231201T120000
DTSTAMP:20260422T022413
CREATED:20231120T140830Z
LAST-MODIFIED:20231120T140830Z
UID:7735-1701424800-1701432000@bifi.es
SUMMARY:Dr. Roch Christian Johnson\, Director Médico de la Fundación Raoul Follereau y Profesor Titular de la Universidad de Abomey-Calavi\, Benín.
DESCRIPTION:Title: Improving Buruli ulcer and leprosy control in Africa \n  \nAbstract: \nNeglected Tropical Diseases (NTD) are a diverse group of communicable diseases prevalent in tropical and subtropical areas. They affect more than a billion people and cost developing economies trillions of dollars every year. The socio-economic consequences are enormous. Of the 20 NTDs\, 12 are endemic in Africa. The co-endemicity of certain diseases; the similarity of the clinical signs as well as the scarcity of financial\, human and temporal resources called for an integrated management of these diseases\, including Buruli ulcer and leprosy. The World Health Organisation road map 2021-2030 aims to accelerate progress towards the prevention\, control\, elimination and eradication of the 20 NTDs. Leprosy elimination and Buruli ulcer control are among the priorities. The target of elimination of leprosy as a Public Health Problem have been achieved since 2000 at the african regional level except the Comoros. Current Buruli ulcer treatment requires 8-weeks of daily rifampicin and clarithromycin\, wound care and\, sometimes\, tissue grafting and surgery. Several clinical trials are currently ongoing and other experimental interventions have been proposed aiming to improve Buruli ulcer treatment by shortening its duration. \nMoreover\, pilot integration experiences have been implemented in different countries\, particularly in Benin and Ivory Coast\, with success\, suggesting that this strategy is effective and efficient in consolidating the achievements of the fight against these diseases. \n  \nOrganizadores \nSantiago Ramón García\, Grupo de Genética de Micobacterias\, Departamento de Microbiología Pediatría\, Radiología y Salud Pública\, Facultad de Medicina\, Universidad de Zaragoza; Fundación Agencia Aragonesa para la Investigación y el Desarrollo (ARAID)\, Zaragoza. \nEmma Sáez López\, Grupo de Genética de Micobacterias\, Departamento de Microbiología Pediatría\, Radiología y Salud Pública\, Facultad de Medicina\, Universidad de Zaragoza. \nConsorcio BLMs4BU (https://blms4bu.org/) \n  \nFRIDAY\, 1st December 2023\, 10:00 h\nSalón de actos del CIBA \n 
URL:https://bifi.es/schedule/dr-roch-christian-johnson-director-medico-de-la-fundacion-raoul-follereau-y-profesor-titular-de-la-universidad-de-abomey-calavi-benin/
LOCATION:Salón de actos del CIBA\, Salón de actos del CIBA\, Zaragoza\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231124T120000
DTEND;TZID=Europe/Madrid:20231124T140000
DTSTAMP:20260422T022413
CREATED:20230912T074821Z
LAST-MODIFIED:20231114T093719Z
UID:7408-1700827200-1700834400@bifi.es
SUMMARY:BIFI TALK: Cristina Mayor Ruiz. IRB Barcelona (Barcelona\, Spain)
DESCRIPTION:BIFI TALK: CRISTINA MAYOR RUIZ \nTitle: Targeted protein degradation: Chasing molecular glues and coping with resistance to degraders \n  \nAbstract: \nTargeted protein degradation is a pharmacological strategy based on drugs (degraders) that destroy proteins by hijacking the intracellular proteolysis machinery. This strategy has garnered significant attention in the last year owing to its potential to modulate the abundance of proteins that are difficult to target with conventional inhibitors. Degraders can be multivalent (PROTACs) or monovalent (molecular glue degraders) depending on the number of chemical warheads. Molecular glue degraders offer a promising strategy for targeting disease-relevant proteins that were previously considered “undruggable”. Mechanistically\, they orchestrate direct protein-protein interactions between a target protein and an E3 ubiquitin ligase.  As a result\, the target protein gets ubiquitinated and then degraded by the proteasome. Despite their great therapeutic potential\, the discovery of molecular glue degraders has been largely serendipitous. I will discuss our efforts to facilitate the rational development of molecular glues. \nIn addition\, many genetic determinants governing degrader efficiency have been mapped in recent years\, bringing important lessons about resistance mechanisms. Our recent chemoproteomics journey aimed at identifying strategies to overcome broad resistance to degraders will be presented. \n  \nFRIDAY\, 24th November 2023\, 12:00 h\nEdificio I+D (Conference room) \n 
URL:https://bifi.es/schedule/bifi-talk-cristina-mayor-ruiz/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231117T113000
DTEND;TZID=Europe/Madrid:20231117T140000
DTSTAMP:20260422T022413
CREATED:20231114T122305Z
LAST-MODIFIED:20231114T122718Z
UID:7726-1700220600-1700229600@bifi.es
SUMMARY:Webinar Digital Language and Communication Training for EU Scientists
DESCRIPTION:Webinar Digital Language and Communication Training for EU Scientists\, Erasmus + project funded by the European Commission (Project No. 2022-1-ES01-KA220-HED-000086749)\, which will take place this coming Friday\, November 17 at 12.30h. \nIn this seminar there will be brief presentations of the consortium\, its objectives and its planned activities\, related to the following topics: \n– Ethnographies of digital science communication practices.\n– Development of digital resources for the training of researchers in professional and public communication of science.\n– Piloting\, validation and implementation of online training\n– Development of the project’s technological infrastructure and training resources. \nPlease find attached th \nTranslated with www.DeepL.com/Translator (free version) program and some infographics about DILAN. \nRegistration is free and can be done at the following link. Attendance will be certified: \nhttps://forms.gle/fPMjUQQWVDq4sGJU7
URL:https://bifi.es/schedule/webinar-digital-language-and-communication-training-for-eu-scientists/
LOCATION:Online
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231109T100000
DTEND;TZID=Europe/Madrid:20231109T120000
DTSTAMP:20260422T022413
CREATED:20230912T075339Z
LAST-MODIFIED:20231103T075156Z
UID:7414-1699524000-1699531200@bifi.es
SUMMARY:II Cycle of young researcher seminars: Pablo Valgañón
DESCRIPTION:“Procesos de reacción-difusión y estrategias de control epidémico”. PABLO VALGAÑÓN \n  \nWednesday\, 8th November\, 2023\n10:00-12:00 h\nSalón de actos.Edificio I+D
URL:https://bifi.es/schedule/ii-cycle-of-young-researcher-seminars-pablo-valganon/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231020T120000
DTEND;TZID=Europe/Madrid:20231020T140000
DTSTAMP:20260422T022413
CREATED:20230912T073949Z
LAST-MODIFIED:20231016T093019Z
UID:7400-1697803200-1697810400@bifi.es
SUMMARY:BIFI TALK: Salvatore Adinolfi. Department of Drug Science and Technology\, University of Turin\, Italy
DESCRIPTION:BIFI TALK: SALVATORE ADINOLFI. Department of Drug Science and Technology\, University of Turin\, Italy \nTitle: The contradictory role of frataxin in Fe-S cluster biogenesis \nAbstract:  \nFrataxin is a small mitochondrial protein whose limited expression impairs Fe-S cluster biogenesis and promotes iron accumulation\, leading to the neurodegenerative Friedreich’s ataxia. Although frataxin role is yet to be completely unraveled\, its involvement as a regulator of the desulfurase activity in the Fe-S cluster biogenesis machinery has been demonstrated for both human frataxin and its bacterial ortholog CyaY. In this frame\, although the human and the bacterial proteins share high homology in their aminoacidic sequence and tridimensional structure\, a dramatic discrepancy has been highlighted by in vitro studies addressing their effect on the Fe-S cluster formation machinery. In particular\, while CyaY slows down the kinetics of Fe-S cluster formation on IscU\, human frataxin has emerged as an activator of Fe-S cluster biogenesis. In this review it will be described all the information to better understand the evolutionary divergence of the frataxin genes. \nIt is difficult to clarify this apparent paradox by studying the process in vitro where the isolated proteins are in an artificial environment or in vivo under non-controlled conditions. To clarify the issue\, we have used a new approach based on metabolomics to study the enzymatic reaction. We followed the enzymatic kinetics ex vivo using bacterial to investigate enzymatic kinetics of IscS and the role that frataxin plays in it. We prove that IscS is inhibited by bacterial frataxin even in this ex vivo condition. We also prove conclusively that iron acts as the effector of the reaction in prokaryotes. This study provides a new powerful tool for the study of iron sulfur cluster biogenesis. \n  \nFRIDAY\, 20th October 2023\, 12:00 h\nEdificio I+D (Conference Room)
URL:https://bifi.es/schedule/bifi-talk-salvatore-adinolfi/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231009T120000
DTEND;TZID=Europe/Madrid:20231009T143000
DTSTAMP:20260422T022413
CREATED:20230926T074307Z
LAST-MODIFIED:20230926T074307Z
UID:7463-1696852800-1696861800@bifi.es
SUMMARY:TALK: Prof.Derek Bowie. McGill University\, Montreal\, Canada
DESCRIPTION:Re-imagining the glutamatergic synapse: From structure-function to neurological disease\nProfessor Derek Bowie. Department of Pharmacology & Therapeutics\, McGill University\, Montreal\, Canada \nAbstract:\nThe Bowie Lab uses a combination of techniques to study ionotropic glutamate receptors (iGluRs)\, GABA-A receptors and more recently\, sodium and potassium channels. All ion-channel families are widespread in the vertebrate brain and fulfill many important roles in healthy individuals as well as being implicated in disease states associated with postnatal development (e.g. autism\, schizophrenia)\, cerebral insult (e.g. stroke\, epilepsy) and aging disorders (e.g. Alzheimer’s disease\, Parkinsonism). We are looking at iGluRs\, GABA-A receptors\, Na+ and K+ channels at two inter-related levels. In molecular terms\, we are examining the events that occur when each ion-channel family is activated with the aim of developing novel therapeutic compounds. At the cellular level\, we are studying the role they fulfill in shaping the behaviour of neuronal circuits and how these processes may be corrected in disease states. The talk will focus on recent work from the lab on a subclass of iGluRs\, called AMPA receptors. \nBiosketch:\nDr. Derek Bowie is a Professor of Pharmacology & Therapeutics at McGill University and co-Director of the Cell Information Systems. The Bowie lab focuses on several major ion-channel families with a special emphasis on their role in neurodevelopmental disorders. Dr. Bowie earned his Ph.D. at the University of London after completing his undergraduate degree at Strathclyde University in Scotland. He then carried out postdoctoral training in France (Université Louis Pasteur)\, Switzerland (Universität Zürich) and the US (National Institutes of Health) before taking a faculty position at Emory University (Atlanta\, GA\, USA). He started his research program at McGill in 2002 and is currently a Full Professor. He was recently a Visiting Professor in Japan (Natl. Institutes for Physiological Sciences). He is the recipient of the Canada Research Chair award in Receptor Pharmacology and has served on numerous national and international advisory panels including IBRO. He also serves/has served on several editorial boards including the Journal of Physiology\, Current Neuropharmacology\, Channels\, Current Opinion in Physiology and Frontiers in Neural Circuits. In 2022\, he co-founded the McGill spin-off company\, Nospharma\, to develop and bring to market therapeutics for the treatment of rare neurological disorders. \n  \n9th October\, 2023 \nSalón de Actos\, Edificio I+D \n12 h
URL:https://bifi.es/schedule/talk-prof-derek-bowie-mcgill-university-montreal-canada/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231004T100000
DTEND;TZID=Europe/Madrid:20231004T120000
DTSTAMP:20260422T022413
CREATED:20230912T074343Z
LAST-MODIFIED:20231003T090647Z
UID:7402-1696413600-1696420800@bifi.es
SUMMARY:II Cycle of young researcher seminars: Patricia Bruñen
DESCRIPTION:Design and synthesis of FMN derivatives for covalent binding to apoflavodoxin from Anabaena. PATRICIA BRUÑEN. \n  \nWednesday\, 4th October\, 2023 \n10:00-12:00 h \nEdificio I+D
URL:https://bifi.es/schedule/ii-cycle-of-young-researcher-seminars-patricia-brunen/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230929T120000
DTEND;TZID=Europe/Madrid:20230929T140000
DTSTAMP:20260422T022413
CREATED:20230912T073406Z
LAST-MODIFIED:20230912T073644Z
UID:7391-1695988800-1695996000@bifi.es
SUMMARY:BIFI TALK: Inmaculada Pérez Dorado\, Instituto de Química-Física Blas Cabrera (CSIC)
DESCRIPTION:BIFI TALK: INMACULADA PÉREZ DORADO\, Instituto de Química-Física Blas Cabrera (CSIC) \n  \nTitle: Host-pathogen interactions in pathogenic mycobacteria. Underlying molecular mechanisms and new ways for antimicrobial development. \nAbstract: \nThe Mycobacterium genus contains over 150 recognized species\, many of which produce infectious diseases in human such as tuberculosis or leprosy\, caused by Mycobacterium tuberculosis (Mtb) and Mycobacterium leprae\, respectively. Human tuberculosis is one of the world’s most devastating human ID responsible of ~1.5 million deaths every year; while leprosy is an IDs associated with permanent deformation\, disability and stigma\, with > 200.000 new cases every year. Our group aims at using structural biology approaches to acquire a deep understanding of biological systems involved in host-pathogen interactions in pathogenic mycobacteria\, as well as finding new ways for antimicrobial development. Our work mainly focuses on the study of the ESX5 secretion system and LysA mycobacteriophage-encoded endolysins. The ESX5 secretion system is a complex molecular machine\, and key virulence factor essential for the viability of pathogenic mycobacteria\, including Mtb. EccC5 is a large ATPase\, and pivotal ESX5 component\, that provides the secretion driving force via ATP hydrolysis. Our structural studies reveal the lack of ATPase activity proposed for the N-terminal DUF domain of EccC5\, which is likely conserved in other ESX systems from mycobacterial and non-mycobacterial species. These results uncover key features of the ESX-dependent secretion mechanism\, and it may open new ways for inhibitor development targeting the EccC5-DUF domain. Bacteriophage endolysins are peptidoglycan hydrolases targeting the bacterial surface that\, when exogenously applied\, can produce a rapid and specific elimination of pathogenic bacteria. In this line\, DS6A-LysA and D29-LysA are complex multidomain endolysins with potential antimicrobial application against pathogenic mycobacteria. Our crystallographic studies of DS6A-LysA and D29-LysA catalytic domains uncovers important aspects of the mechanism of cell-wall binding and hydrolysis by these endolysins\, knowledge that is key for their potential application as specific antimicrobials. \n  \nFRIDAY\, 29 September 2023\, 12:00 h\nEdificio I+D \n 
URL:https://bifi.es/schedule/bifi-talk-inmaculada-perez-dorado-instituto-de-quimica-fisica-blas-cabrera-csic/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230602T120000
DTEND;TZID=Europe/Madrid:20230602T140000
DTSTAMP:20260422T022413
CREATED:20230531T093914Z
LAST-MODIFIED:20230531T093914Z
UID:7338-1685707200-1685714400@bifi.es
SUMMARY:BIFI TALK: Horacio López Menéndez
DESCRIPTION:Title: Connectivity as a tool to investigate hydro-geomorphic systems: A river delta case study. \nAbstract: \n  \n  \nFRIDAY\, 2nd June 2023\, 12:00 h\nAula: Edificio I+D
URL:https://bifi.es/schedule/bifi-talk-horacio-lopez-menendez/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230510T100000
DTEND;TZID=Europe/Madrid:20230510T120000
DTSTAMP:20260422T022413
CREATED:20230505T082658Z
LAST-MODIFIED:20230505T083023Z
UID:7313-1683712800-1683720000@bifi.es
SUMMARY:II Cycle of young researcher seminars: Irene Oliván Muro
DESCRIPTION:“Biofilms en Anabaena sp. PCC7120: estudio de los factores que afectan a su desarrollo y regulación por proteínas FUR”. IRENE OLIVÁN MURO \nWednesday\, 10th May\, 2023 \n10:00-12:00 h \nAula del Edificio I+D
URL:https://bifi.es/schedule/ii-cycle-of-young-researcher-seminars-irene-olivan-muro/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230505T120000
DTEND;TZID=Europe/Madrid:20230505T140000
DTSTAMP:20260422T022413
CREATED:20230505T083951Z
LAST-MODIFIED:20230505T084049Z
UID:7319-1683288000-1683295200@bifi.es
SUMMARY:BIFI TALK: Alejandro Tejedor ( BIFI )
DESCRIPTION:Title: Connectivity as a tool to investigate hydro-geomorphic systems: A river delta case study. \nAbstract: \nConnectivity plays a crucial role in natural and engineered systems\, driving and resulting from various processes. For example\, sediment fluxes shape the landscape\, creating preferential paths for water and sediment transport\, ultimately leading to channelized flows that affect the system’s response to changing forcings. Research in geomorphic systems has focused on understanding the emergent connectivity structures and their impact on system dynamics. To this end\, network theory provides a suitable mathematical framework for quantitatively characterizing connectivity patterns. In this presentation\, I will use river deltas as a case study to demonstrate how an integrated approach\, combining network theory\, remote sensing\, and modeling tools\, can enhance our understanding of the structure and dynamics of geomorphic systems. Specifically\, I will showcase how analyzing river delta channel networks can help solve the inverse problem of inferring process from form\, classify and compare river deltas\, and predict their dynamic response to different forcing scenarios. \n  \nFRIDAY\, 5th DECEMBER 2023\, 12:00\nConference room: Edificio I+D
URL:https://bifi.es/schedule/bifi-talk-alejandro-tejedor-bifi/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230308T100000
DTEND;TZID=Europe/Madrid:20230308T120000
DTSTAMP:20260422T022413
CREATED:20230303T134213Z
LAST-MODIFIED:20230303T134737Z
UID:7269-1678269600-1678276800@bifi.es
SUMMARY:II Cycle of young researcher seminars: Sonia Hermoso Durán
DESCRIPTION:“Inteligencia artificial aplicada a TLB y proteomas: mejorando la detección precoz y la vigilancia del paciente para el diagnóstico clínico”. SONIA HERMOSO DURÁN \nWednesday\, 10th March\, 2023 \n10:00-12:00 h \nAula del Edificio I+D
URL:https://bifi.es/schedule/ii-ciclo-de-seminarios-de-jovenes-investigadores-sonia-hermoso-duran/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20230125
DTEND;VALUE=DATE:20230128
DTSTAMP:20260422T022413
CREATED:20221102T093942Z
LAST-MODIFIED:20230111T113621Z
UID:7119-1674604800-1674863999@bifi.es
SUMMARY:XI National Conference BIFI 2023
DESCRIPTION:The XI National Conference BIFI 2023 (http://bifi23.bifi.es) of the Institute for Biocomputation and Physics of Complex Systems  (BIFI) aims at giving all participants the chance to disseminate their work\, and at the same time strengthening existing collaborations or establishing new ones within the different research lines promoted by the BIFI. \nThe format of the congress will include plenary sessions\, with invited and contributed talks\, as well as the corresponding poster sessions. \nMAIN TRACKS: \n\nBiochemistry\, Molecular and Cellular Biology\nPhysics\nBiophysics\nComputation\n\nCALL FOR COMMUNICATIONS \nResearchers from any Institution are warmly invited to attend the meeting\, and submit scientific communications related to the Main Tracks of the event. We could limit the attendees number due to a capacity issue at the conference rooms\, so that\, if necessary\, we might reject applications to participate. \nIMPORTANT DATES \nDates of the Conference: January 25th – January 27th\, 2023.\nRegistration deadline: December 2nd\, 2022.\nAbstract submission deadline: December 2nd\, 2022. \nVENUE \nConference Room\, Edificio I+D\, Campus Río Ebro.
URL:https://bifi.es/schedule/xi-national-conference-bifi-2023/
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221214T100000
DTEND;TZID=Europe/Madrid:20221214T120000
DTSTAMP:20260422T022413
CREATED:20221212T095224Z
LAST-MODIFIED:20221212T095224Z
UID:7154-1671012000-1671019200@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: ANA JIMÉNEZ ALESANCO
DESCRIPTION:“Drug discovery for inhibiting Bacteroides fragilis toxin: from a chemical screening to an animal model”. ANA JIMÉNEZ ALESANCO \nWednesday\, 14 December 2022 \n10:00-12:00 h \nSalón de Actos Edificio I+D
URL:https://bifi.es/schedule/i-cycle-of-young-researcher-seminars-in-the-bio-area-ana-jimenez-alesanco/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221123T100000
DTEND;TZID=Europe/Madrid:20221123T120000
DTSTAMP:20260422T022413
CREATED:20221118T090141Z
LAST-MODIFIED:20221118T090956Z
UID:7134-1669197600-1669204800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS  IN THE BIO AREA: Mario Tovar Calonge
DESCRIPTION:“Forecasting perturbations on mycobacterium tuberculosis transmission with mathematical models: From COVID19-TB syndemics to the evaluation of new vaccines”. MARIO TOVAR CALONGE \nWednesday\, 23 November 2022 \n10:00-12:00 h \nSalón de Actos Edificio I+D
URL:https://bifi.es/schedule/i-ciclo-de-seminarios-jovenes-investigadores-en-el-area-bio-mario-tovar-calonge/
LOCATION:Salon de actos del edificio I+D
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221005T093000
DTEND;TZID=Europe/Madrid:20221005T113000
DTSTAMP:20260422T022413
CREATED:20221025T124545Z
LAST-MODIFIED:20221118T091225Z
UID:7094-1664962200-1664969400@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: ANDRÉS MANUEL GONZÁLEZ RAMÍREZ
DESCRIPTION:“Bases estructurales de la Core 1 sintasa”. ANDRÉS MANUEL GONZÁLEZ RAMÍREZ \nWednesday\, 5 October 2022 \n9:30-11:30 h \nSalón de Actos Edificio I+D
URL:https://bifi.es/schedule/i-cycle-of-seminars-young-researchers-in-the-bio-area-andres-manuel-gonzalez-ramirez/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220914T100000
DTEND;TZID=Europe/Madrid:20220914T120000
DTSTAMP:20260422T022413
CREATED:20220915T120524Z
LAST-MODIFIED:20221118T091314Z
UID:7004-1663149600-1663156800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: Javier Macías León
DESCRIPTION:“Estudio de la acción protectora frente a infecciones fúngicas invasivas de un nanobody dirigido al sitio activa de beta-1\,3.glucanosiltransferasas”. JAVIER MACÍAS LEÓN \nThursday\,14 september\,2022 \n10:00-12:00 h \nAula Edificio I+D
URL:https://bifi.es/schedule/i-ciclo-de-seminarios-jovenes-investigadores-en-el-area-bio-javier-macias-leon/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220616T100000
DTEND;TZID=Europe/Madrid:20220616T120000
DTSTAMP:20260422T022413
CREATED:20220615T063247Z
LAST-MODIFIED:20221118T091346Z
UID:6856-1655373600-1655380800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: PABLO FERNÁNDEZ GARRIDO
DESCRIPTION:“Nuevos métodos en autoorganización e interfases: experimentación\, análisis y simulación”. PABLO FERNÁNDEZ GARRIDO \npablo_f_garrido_a4 \nThursday\,16 June 2022\n10:00-12:00 h\nAula Edificio I+D
URL:https://bifi.es/schedule/i-cycle-of-seminars-young-researchers-bio-area-pablo-fernandez-garrido/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220607T090000
DTEND;TZID=Europe/Madrid:20220609T180000
DTSTAMP:20260422T022413
CREATED:20211027T125134Z
LAST-MODIFIED:20220503T114702Z
UID:6547-1654592400-1654797600@bifi.es
SUMMARY:The International BIFI 2022 Conference
DESCRIPTION:The  International BIFI 2022 Conference will take place online from February 7th to 9th\, 2022. On this occasion the Conference will be focused on the Science of Covid-19: from molecular drug design to data-driven epidemiological models.  \nIn order to ease attendance\, this year’s conference will be entirely hosted online. \nEvery two years the Institute organizes an international conference around its research areas. This is the case of 2022 when we will be holding the BIFI 2022 International Conference which will focus around what we could call the Science of Covid-19. As we well know at this time\, the subject is highly topical and possibly expected\, but given the massive impact to our societies and its relation to the core activities of our institute\, it is also natural choice for 2022. We hope this occasion will serve to consolidate knowledge on the topic\, bring new insights and tools to it\, and also to fill some gaps and open new research paths. The Conference aims at providing a forum to discuss the latest advances and insights in the study of this pandemic. All topics that fit within the science of COVID-19 from a complexity\, biological or interdisciplinary point of view are welcome. \nOn the website of the event (http://bifi22.bifi.es/) to be announced all the necessary information including the access link in due time.
URL:https://bifi.es/schedule/the-international-bifi-2022-conference/
LOCATION:Online
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220601T100000
DTEND;TZID=Europe/Madrid:20220601T120000
DTSTAMP:20260422T022413
CREATED:20220610T112250Z
LAST-MODIFIED:20221118T091419Z
UID:6848-1654077600-1654084800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: Cristina Sarasa Buisán
DESCRIPTION:Seminar 2: FurC/PerR de Anabaena sp. PCC7120\, un regulador transcripcional que integra dos niveles de respuesta al estrés oxidativo. CRISTINA SARASA BUISÁN \ncristina-sarasa-buisan_v4_a4 \nWednesday\, 1 June 2022\n10:00 h\nAula del Edificio I+D
URL:https://bifi.es/schedule/i-ciclo-de-seminarios-jovenes-investigadores-area-bio-cristina-sarasa-buisan/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20220526
DTEND;VALUE=DATE:20220528
DTSTAMP:20260422T022413
CREATED:20220615T065125Z
LAST-MODIFIED:20220615T065125Z
UID:6882-1653523200-1653695999@bifi.es
SUMMARY:Congreso virtual "Géneros Digitales y Ciencia Abierta"
DESCRIPTION:Los días 26 y 27 de mayo se celebrará el Congreso virtual “Géneros Digitales y Ciencia Abierta”. Este congreso es una de las actividades realizadas en el marco del proyecto de investigación PID2019-105655RB-I00 (IIPP María José Luzón Y Carmen Pérez-Llantada). En el congreso se debatirá sobre el impacto de los rápidos desarrollos tecnológicos de la Web 2.0 y el fomento de la ciencia en abierto en las actuales prácticas de comunicación y difusión de la ciencia. \nIntervendrán como conferenciantes plenarios: \nProf. Vijay Bhatia (The Chinese University of Hong Kong)\nProf. Christoph Hafner (City University of Hong Kong)\nProf. Benedikt Fecher (Alexander von Humboldt Institute for Internet and\nSociety)\nProf. Emeritus John M. Swales (University of Michigan\, US) \nMás información sobre el congreso: http://genci.unizar.es/conference/ \nInscripción (gratuita) en la siguiente dirección:\nhttp://genci.unizar.es/conference/
URL:https://bifi.es/schedule/congreso-virtual-generos-digitales-y-ciencia-abierta/
LOCATION:Online
CATEGORIES:Congresses
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220513T160000
DTEND;TZID=Europe/Madrid:20220513T180000
DTSTAMP:20260422T022413
CREATED:20220610T111418Z
LAST-MODIFIED:20221118T091455Z
UID:6842-1652457600-1652464800@bifi.es
SUMMARY:I CYCLE OF YOUNG RESEARCHER SEMINARS IN THE BIO AREA: Helena García Cebollada
DESCRIPTION:Seminar 1: Protposer: a web server for rational stabilization of proteins. HELENA GARCÍA CEBOLLADA \nseminariohelenagarcia_panoramica-2\nFriday 13 May 2022\n16:00 horas\nSalón de actos del Edificio I+D\n¡¡Followed by Happy hour!!
URL:https://bifi.es/schedule/i-ciclo-de-seminarios-jovenes-investigadores-area-bio-helena-garcia-cebollada/
LOCATION:Edificio Institutos I+D\, Mariano Esquillor\, 50018 Zaragoza\, Zaragoza\, Zaragoza\, 50018\, España
CATEGORIES:Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220404T083000
DTEND;TZID=Europe/Madrid:20220404T150000
DTSTAMP:20260422T022413
CREATED:20220330T072604Z
LAST-MODIFIED:20220330T072604Z
UID:6784-1649061000-1649084400@bifi.es
SUMMARY:Jornada de Bioingeniería y Biotecnología
DESCRIPTION:El próximo lunes 4 de abril se celebrará la Jornada de Bioingeniería y Biotecnología\, organizada por los Institutos Universitarios de Investigación (IUIs) de la Universidad de Zaragoza. \nEl encuentro acomete un doble objetivo: \n1) difundir e intercambiar el significativo conocimiento que se genera en la investigación de los institutos en el ámbito de la bioingeniería y biotecnología; \n2) generar nuevas colaboraciones multidisciplinares entre distintos grupos con experiencia y capacidades diferentes. \nLa jornada se celebrará en el Salón de Actos del Edificio I+D del Campus Río Ebro y se podrá seguir presencialmente u online\, registrándose previamente en el siguiente enlace Zoom: \nhttps://zoom.us/webinar/register/WN_gYFdy2gDTcKK2U1LgIib6A (tras la inscripción\, se recibirá un correo electrónico de confirmación con información para unirse al seminario web). \nEl programa de la Jornada puede consultarse jornada-bioingeniera-y-biotecnologa_20200404
URL:https://bifi.es/schedule/jornada-de-bioingenieria-y-biotecnologia/
CATEGORIES:Events
END:VEVENT
END:VCALENDAR