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BIFI TALKS: Sylvie Callegari, del Eliza Hall Institute of Medical Research, Australia Title: Activating PINK1 to treat Parkinson’s disease Abstract PINK1, a protein linked to Parkinson's disease, is a ubiquitin kinase that accumulates on the outer membrane of damaged mitochondria. Upon accumulation, PINK1 becomes activated and phosphorylates ubiquitin, generating a unique phospho-ubiquitin signal that triggers […] |
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BIFI TALK: José Manuel Martín García, del Instituto Blas Cabrera, CSIC, Madrid Title: Time-resolved structural studies with serial crystallography: A new frontier in biomedical research. Abstract Structural biology, especially X-ray crystallography, has significantly advanced our understanding of diseases by revealing the 3D structures of proteins. However, traditional X-ray crystallography encounters challenges, such as difficulties in obtaining […] |
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