BIFI TALK: David Fernández-Antorán. Gurdon Institute, Cambrigde and ARAID-IIS Aragón

Title: Epithelioids: Long-term and self-maintained primary 3D cultures to study tissue behaviour in vitro

Abstract

This talk will introduce “Epithelioids,” a novel 3D primary epithelial culture system that enables the long-term, self-sustaining growth of tissues derived from both normal and tumour samples. Epithelioids maintain the proliferation, differentiation, and structural integrity of adult epithelial tissues, faithfully replicating the complex interactions between different cell types, including the immune system. With their high genomic stability, Epithelioids are particularly suited for studying long-term tissue responses to clinical treatments and environmental factors. This system offers a powerful tool for investigating tumour-normal tissue interactions and is ideal for research into stem cell dynamics and cancer biology, including tumour responses to radio and chemotherapies.

FRIDAY, 18th October 2024, 12:30 h
Edificio I+D (Conference room)