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1:00 pm
BIFI TALK: Athi N Naganathan, Indian Institute of Technology Madras (IITM), Chennai, India
BIFI TALK: Athi N Naganathan, Indian Institute of Technology Madras (IITM), Chennai, India Title: Conformational Tuning as a Mechanism to Determine Specificity and Promiscuity Abstract: Paralogous proteins confer enhanced fitness to organisms via complex sequence-conformation codes that shape functional divergence, specialization, or promiscuity. Here, we resolve the underlying mechanism of promiscuous binding versus partial sub-functionalization […]
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