Title: Improving Buruli ulcer and leprosy control in Africa   Abstract: Neglected Tropical Diseases (NTD) are a diverse group of communicable diseases prevalent in tropical and subtropical areas. They affect more than a billion people and cost developing economies trillions of dollars every year. The socio-economic consequences are enormous. Of the 20 NTDs, 12 are endemic in Africa. The co-endemicity of certain diseases; the similarity of the clinical signs as well as the scarcity of financial, human and temporal resources called…

Miguel Campos, Bioflora, Escuela Politécnica Superior, Huesca Comparative and functional genomics: a comprehensive approach to understanding the evolution of the Brachypodium annualis complex Wednesday, 7 th February , 10 h Sala de conferencias. Edificio I+D, Mariano Esquillor S/N.  

On March 22 at 12:30 a scientific dissemination event will take place at the Agri-Food Market at the San Francisco Campus (next to the campus pond, C. Pedro Cerbuna, 12) to give visibility to the BIOPHYSICS knowledge area. This day is part of the Biophysics Week (https://www.biophysics.org/biophysics-week#/) organized annually by the Biophysical Society of the United States with events around the world. The event will consist of two informal talks by two researchers from the Institute of Biocomputation and Physics…

BIFI TALK: Narimantas Cenas, Vilnius University of Lituania Title: Single- and two-electron reduction of nitroaromatic compounds by flavoenzymes: mechanisms and implications for cytotoxicity Wednesday, 8th May 2024, 12:30 h Edificio I+D (Conference room)

M José Luzón and Carmen Pérez-Llantada (Digital Science Lab Computing and Data ScienceBIFI) cordially invite you to participate in the webinar "Digital Genres and Open Science", which will take place on Tuesday, 14 May 2024, from 10:00 to 13:00 (Madrid time). The webinar will consist of three sessions dedicated to the presentation of our findings on digital genres for the promotion and dissemination of science. This presentation will be followed by a multidisciplinary round table (in Spanish): Oportunidades y retos…

BIFI TALK: Athi N Naganathan, Indian Institute of Technology Madras (IITM), Chennai, India Title:  Conformational Tuning as a Mechanism to Determine Specificity and Promiscuity Abstract: Paralogous proteins confer enhanced fitness to organisms via complex sequence-conformation codes that shape functional divergence, specialization, or promiscuity. Here, we resolve the underlying mechanism of promiscuous binding versus partial sub-functionalization by studying paralogous Acyl-CoA Binding Proteins (ACBPs) from Plasmodium falciparum. Combining experiments and simulations on two of the paralogs, A16 and A749, we show that…

BIFI-Talk: Sara García Linares. Universidad Complutense de Madrid. Title: Design of nanoreactors for plastic depolymerization based on pore-forming toxins Abstract Petroleum-based plastics are durable and accumulate in all ecological niches. Approximately 80% of waste objects are made of macroplastics, with most ending up dumped into the oceans. PET (polyethylene terephthalate) is the primary component in many synthetic fibers and water bottles, comprising 14.4% of total plastic waste. Our work focuses on improving biotechnological processes for PET degradation by designing more…