Tittle: Networks Virology. Learning from SARS-CoV-2 Abstract: Viruses are reproductive machineries formed mainly by genetic material (RNA or DNA) and proteins. In general, these proteins interact with specific proteins of the host forming vast networks of virus-host protein-protein interactions (PPI). Although a virus may infect mainly an organ or system of the host, the damages can propagate beyond it, transforming the affection into a multiorganic/multifunctional one. This is the case of SARS-CoV-2, which makes COVID-19 a multiorganic disease affecting a…

Title: From structure to mechanisms of Zika virus induced neurodevelopmental disease Abstract: Zika virus (ZIKV) infection was declared a global threat for public health due to its association with congenital neurodevelopmental birth defects, such as microcephaly, a rare medical condition characterized by a significant decrease in brain size. ZIKV infection delays cell cycle progression and induces cell death of neural progenitor cells (NPCs), leading to reduced production of neurons. Despite the enormous basic and clinical research efforts, no specific therapy…

Transformando el Consejo de Seguridad Nuclear para mejorar la seguridad nuclear y la protección radiológica. El papel del Consejo de Seguridad Nuclear (CSN) en el contexto de la situación actual será el tema central de la conferencia. La renovación en la que se encuentra inmerso dicho organismo pretende aportar mas transparencia con el fin de generar mas confianza y seguridad en la sociedad. En este sentido la ciencia ciudadana podría jugar un papel importante. Dia: 28 de Mayo 2021, Hora: 12…

Title: Ecology of Online Social Systems Abstract Online social networks have significantly changed global communication dynamics and, in general, the way we interact. Every day our brain is flooded by information coming from a plethora of sources and this cognitive bottleneck translates into hyper-competition for a scarce resource: our attention. This pressure, in turn, pushes information producers to mutualistically interact with specific memes and actors, seeking the virality of their messages. Finally, memes’ chances to persist and spread are subject to…

Title: Neurodegenerative proteinopathies: implications and molecular mechanisms of MOK signaling kinase in neuroinflammatory responses. Abstract: Neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Amyotrophic lateral sclerosis (ALS) are incurable proteinopathies characterized by progressive neuronal loss, aggregation and deposition of specific proteins in the central nervous system (CNS) and sustained neuroinflammation. In the last few years, it has become increasingly accepted that such protein aggregates have a principal role in triggering neurotoxic immune responses. Still, and particularly for ALS, the molecular mechanisms and proteins…

Title: Approaches from physics of complex systems to model the brain in vitro Abstract Neuroengineering is one of the most exciting techniques in modern neuroscience. The capacity to design controlled environments for the neurons to grow and interconnect is opening new frontiers for the development of accurate in vitro systems that reproduce complex brain functions. In this talk, I will present relatively simple yet surprisingly enlightening experimental designs that are analyzed in the context of dynamical systems and complex networks.…

Title: Glycochemistry and Molecular Recognition: Rational and Combinatorial Approaches Abstract: Carbohydrates participate in a large variety of molecular recognition processes of biological relevance, involving both proteins receptors, enzymes and nucleic acid fragments. Understanding how these later bio-molecules interact with glycosides represents a fundamental issue in chemical biology with far reaching implications in fundamental biology, biotechnology or drug design. On the other hand, the acknowledgment of the relevance of glycoconjugates in biology has run parallel to the development of new chemical methods…

CIENCIA DIGITAL: SOSTENIBLE, TRANSFORMATIVA Y TRANSVERSAL. RETOS Y PROSPECTIVA  programa-ciencia-digital_webinar_22-feb-2022_c Martes 22/02/2022 Hora: 10.30-12.00h Zoom webinar: https://zoom.us/j/92996415947